The Long Term Impact of Over Eating

When you are enjoying what you’re eating, overeating is an easy act to commit. Recent studies have shown that overeating can lead to EVEN MORE EATING, which may get in the way of your weight loss goals. Why does this happen? Research has found that the feeling of fullness becomes blocked in your brain once the body eats too many calories.

Uroguanylin is the hormone produced once your brain receives the information that you are full. But if you overeat, the hormone stops producing and your brain no longer receives the information that you’ve eaten enough so you may continue to eat more. This happens because overfeeding stresses the endoplasmic reticulum in your small intestine, an organelle responsible for much of the body’s hormone production. When you overeat, the endoplasmic reticulum becomes stressed and stops producing hormones that tell your brain that your body has consumed enough calories.

A study on lean and obese mice showed that it is not obesity causing the issue, it’s purely the cease of the production of uroguanylin when too many calories are consumed. The study was unable to find out how much food is too much, but what is known is that it takes 20 minutes for the brain to realize that your stomach is full. So in order to avoid overeating and consumption of unneeded calories, here are some suggestions to prevent yourself from overeating:

  • Stay hydrated – If your body isn’t properly hydrated, your brain will think that you are more hungry than you actually are because you are in fact thirsty. Drink at least 8 oz. of water before eating a meal to avoid overconsumption of calories.
  • Eat Slowly – As said before, it takes at least 20 minutes for your brain to realize it is full. So eat slowly and enjoy your food! Listen to your body, you will know when you have consumed enough calories.
  • Eat the right foods – Foods that are high in water content but low in calories, such as fruits or vegetables, are great because they will help keep your body hydrated. And because they are low in calories, but high in bulk, it is easier for your body to send the information to your brain that you’ve eaten enough.

Study: Thomas Jefferson University. “Broken calorie sensing pathway: How overeating may lead to more eating.” ScienceDaily. ScienceDaily, 15 June 2016. <>.

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